Dr. Khalida Sabeur

Name: Khalida Sabeur Address: 2123 Tupper Hall, Department of Population Health and Reproduction University of California, Davis, California 95616. Telephone: 530-752-5331 Fax: 530-752-4278 E-mail: ksabeur@ucdavis.edu

• Education
  1. B.Sc., Biology, University Mohammed V, Morocco, 1976
  2. D.E.A., Physiology, University Mohammed V, Morocco, 1977
  3. M.Sc., Physiology, University of Minnesota, 1982.
     
  4. Ph.D., Endocrinology, University of California, 1990.
     
  
   
• Professional Experience:
  1. 1998-Present: Research Scientist, Department of Population Health and Reproduction, University of California, Davis, CA, USA.
  2. 1997-1998: Post-Graduate Researcher, Loeb Research Institute, Ottawa.Canada
  3. 1993-1997: Post-Graduate Researcher, Reproductive Biology, University of California, Davis, CA, USA
  4. 1990-1991: Postdoctoral fellow, Endocrinology, University of California, Davis.
  5. 1985-1990: Graduate Researcher and Teaching Assistant, Reproductive Endocrinology, University of California, Davis.
  6. 1982-1985: Researcher and Lecturer, Reproduction-Physiology, Agronomic and Veterinary Institute, Rabat, Morocco
  7. 1980-1982: Graduate Researcher, Reproductive Physiology, University of Minnesota, Saint-Paul.
  8. 1977-1980: Teaching and Administrative Assistant, Physiology, Biological Sciences, Agronomic and Veterinary Institute, Rabat, Morocco.
  
   
• Honors and Awards:
  1. 1997-1998: Lalor Foundation Postdoctoral Fellowship, Loeb Research Institute
  2. 1996-1997: Mellon Foundation Postdoctoral Fellowship, University of California, Davis,
  3. 1990-1991: Postdoctoral fellowship RTG-NIDRR, University of California, Davis,
  4. 1989-1990: Austin Eugene Lyons Graduate Scholarship,
  5. 1985-1987: US Agency of International Development Scholarship
  6. 1980-1982: US Agency of International Development Scholarship
  
   
• Professional and Scientific Memberships:
  1. 1998-present: Member, Society for the Study of Reproduction
  2. 2001-present: Member, WAND, Women's action for New Directions
  3. 2005: Member, International Society for Stem Cell Research
  
   
• Grants:
  1. 2005: "Gene delivery and Gene silencing in human embryonic stem cells". Office of Research Internal Funding Programs, UC Davis. submitted, K. Sabeur.
  2. 2005: "Application of sperm-mediated gene transfer in the horse". Center for Equine Health, University of California, Davis. submitted 07/05-07/08. K. Sabeur and B.A. Ball.
  3. 2003-2005: "Molecular and functional characterization of an equine sperm protein responsible for oviductal adhesion". Center for Equine Health, University of California, Davis. 07/03-06/05. K. Sabeur and B.A. Ball.
  4. 2001-2004: "Effects of oxidative stress and osmotic stress on equine spermatozoa relative to cryopreservation". USDA-NRICGP. 10/01- 9/04. B.A. Ball, S.A.Meyers and K. Sabeur
  5. 2000-2001: "Development of Nonsurgical Sterilization Procedures for Canine Population Control". The Kennet Scott Charitable Trust. 9/01-8/03. B.A.Ball, I.K.M.Liu and K. Sabeur
  6. 1999-2000: "Development of Nonsurgical Sterilization Procedures for Canine Population Control". The Kennet Scott Charitable Trust. 10/99-10/00. B.A. Ball, I.K.M.Liu and K. Sabeur
  
   
• List of Publications
  In Journals:
  1. Sabeur, K. Ball. BA. and Banfi B. NADPH Oxidase in Equine Testis and Spermatozoa. (in preparation 2005)
      
  2. Sabeur, K., Corbin CJ, Conley AJ, and. Ball BA. Cloning of a Full Length cDNA encoding for a Novel Testis Specific Equine Serine-Threonine Kinase (in preparation, 2005)
      
  3. Sabeur K, Nett TM, Liu IW, and Ball BA. Effects of Gonadotropin-releasing Hormone conjugated to Pokeweed antiviral protein (GnRH-PAP) on Reproductive Function of male dogs before and after puberty (in preparation, 2005).
      
  4. Sabeur K, Ball BA, Nett TM, Ball HH, Liu IK. Effect of GnRH conjugated to pokeweed antiviral protein on reproductive function in adult male dogs. Reproduction. 2003; 125(6):801-6.
      
  5. Baumber J, Sabeur K, Vo A, Ball BA. Reactive oxygen species promote tyrosine phosphorylation and capacitation in equine spermatozoa. Theriogenology. 2003 Oct 15;60(7):1239-47.
      
  6. Ball BA, Gravance CG, Wessel MT, Sabeur K. Activity of angiotensin-converting enzyme (ACE) in reproductive tissues of the stallion and effects of angiotensin II on sperm motility. Theriogenology. 2003 Feb; 59(3-4):901-14.
      
  7. Sabeur K, Foristall K., and Ball B.A. 2002. Characterization of PH-20 in canine spermatozoa and testis. Theriogenology, 57(2): 977-87
      
  8. Baumber J, Vo A., Sabeur K., and Ball B.A. 2002. Generation of reactive oxygen species by equine neutrophils and their effect on motility of equine spermatozoa. Theriogenology 57(3):1025-33.
      
  9. Sabeur K., and Ball B.A. 2001. Characterization of Angiotensin-Converting Enzyme in canine testis. Reproduction, 122, 139-146.
      
  10. Sabeur K, Vo, A., and Ball B.A. 2000. Effects of Angiotensin II on the acrosome reaction in equine spermatozoa. J. Reprod. Fert. 120, 135-142.
       
  11. Sabeur K., Cherr G.N., Yudin A.I., VanderVoort C.A., and Overstreet J.W. 1998. Hyaluronic acid enhances induction of the acrosome reaction of human sperm through interaction with the PH-20 protein. Zygote 6, 103-111.
       
  12. Ming-Wen Li., Yudin A.I., Cherr G.N., VanderVoort C.A., Sabeur K., Primakoff P., and Overstreet J.W. 1997. Inhibition of sperm hyaluronidase and cumulus penetration by flavonoids. Biol. of Reprod. 56, 1383-1389.
       
  13. Sabeur K., Cherr G.N., Yudin A. I, Primakoff P., and Overstreet J. W. 1997. The PH-20 protein in human sperm. J. Andrology 18 (2) 151-158.
       
  14. Sabeur K., Edwards D.P, and Meizel S. 1996. Plasma membrane progesterone receptor(s) in human sperm. Biol. of Reprod. 54, 993-1001.
       
  15. Sabeur K. and Meizel S. 1995. Importance of bicarbonate to the progesterone-initiated human sperm acrosome reaction. J. Andrology 16 (3): 266-271.
       
  16. Sabeur K., King.D.B. and Entrikin R.K. 1993. Differential effects of dexamethasone and methimazole on thyroid hormones in dystrophic chicken. Life Sciences 52 (13): 1149-59.
  
    In Conferences:
  1. Sabeur K, Nett TM, Liu IKM, and Ball BA. Effects of Gonadotropin-Releasing Hormone conjugated to pokeweed antiviral protein (GnRH-PAP) on reproductive function of male of male dogs before and after puberty. Presented at the 2nd International ACCD Symposium - Breckenridge, Colorado, June 24-27, 2004
      
  2. Sabeur K, Ball BA, Krause K-H, Banfi B. NADPH oxidase (NOX5) in equine spermatozoa and testis. Presented at the 37th annual meeting of the Society for the Study of Reproduction, Vancouver, Canada, Aug 2004. Biol Reprod 70 (Suppl 1): 129
      
  3. Sabeur K, Nett TM, Liu IW, and Ball BA. Effects of Gonadotropin-releasing Hormone conjugated to Pokeweed antiviral protein (GnRH-PAP) on Reproductive Function of male dogs before and after puberty. Presented at the Future of Male Contraception, Seattle, Washington, Sept 29- Oct 2, 2004
      
  4. Sabeur K, Ball BA, Nett TM, Ball HB, Liu IKM. A gonadotropin-releasing hormone agonist conjugated to pokeweed antiviral protein disrupts reproductive function in male dogs. Biol. Reprod. 64: Suppl 1: 366. Presented at the 34th annual meeting of the Society for the Study of Reproduction, Ottawa, Canada, Aug 2001
      
  5. Sabeur K, Foristal K, and Ball B.A. Characterization of PH-20 in canine spermatozoa. Biol Reprod 62: Suppl 1: 131. Presented at the Third International Symposium: The Molecular and Cellular Biology of the Egg and Embryo Extracellular Matrix. Lake Tahoe, CA, Aug 2000.
      
  6. Sabeur K and Ball B.A. 2000. Characterization of Angiotensin-Converting Enzyme in canine testis. Biol Reprod 62: Suppl 1: 327. Presented at the 33rd annual meeting of the Society for the Study of Reproduction, Madison,WI, Aug 2000.
      
  7. Sabeur K, Gravance C, and Ball B.A. Effects of Angiotensin II on motility in equine sperm. Biol Reprod 60: Suppl 1: 136. Presented at the 32nd annual meeting Society for the Study of Reproduction, Washington State University, Pullman, WA, Aug 1999.
      
  8. V.L. Trudeau, S. Chiu1, K. Lariviere, M. MacMillan, D. Crump, K. Sabeur, P.T. Bosma, K. Docherty, J.D.D. Bishop, L. Maler, G. Drouin and I.G. Priede. Multiple Glutamate decarboxylases (GAD) likely arose because of an early gene duplication event. Neurosciences. 1999.
      
  9. Sabeur K, Edwards D.P, and Meizel S. 1995. Plasma membrane progesterone receptor(s) in human sperm. Biol. Reprod.Suppl. 1, 52: 60.
      
  10. Sabeur K. and Meizel S. The progesterone-initiated human sperm acrosome reaction: Importance of Bicarbonate. Programs and Abstracts. Presented at the 76th annual meeting of the Endocrine Society, Los Angeles, CA, June 1994.
       
  11. Meizel S., Sunshine C., Sabeur K., and Turner K.O. Studies of human sperm with a progesterone receptor photoaffinity ligand. Mol. Biol. Cell 4, 417a: 2421. 1993
       
  12. Sabeur K. King D.B., and Entrikin R.K. Thyroid hormones in muscular dystrophy of the chicken: Effect of dexamethasone and methimazole. FASEB J. 5, A: 1593. Presented at the FASEB meeting, Atlanta, GA, 1991.
       
  13. Sabeur K. and Adams T.E. Gonadotrope and testicular function in ram lambs: Effect of active immunization against GnRH and pulsatile delivery of a GnRH agonist. Presented at the Proceedings of Western Section of the American Society of Animal Science, 40: 324-327. 1989.
       
  14. Wheaton J.E., Sabeur K., and Mullet M.A. . Frequent gonadotropin-releasing hormone (GnRH) injections induce estrus and ovulation in progesterone treated anestrous ewes. Biol. Reprod. Suppl. 26:116A. 1982.